BDBM50459076 CHEMBL4203024

SMILES: NC(=N)NC(=O)c1nc(-c2ccc(cc2)C(F)(F)F)c(nc1N)N1CCCCCC1

InChI Key: InChIKey=DJXOPWDCWQNTGK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator/surface receptor (Homo sapiens (Human))	BDBM50459076 (CHEMBL4203024) Show SMILES NC(=N)NC(=O)c1nc(-c2ccc(cc2)C(F)(F)F)c(nc1N)N1CCCCCC1 Show InChI InChI=1S/C19H22F3N7O/c20-19(21,22)12-7-5-11(6-8-12)13-16(29-9-3-1-2-4-10-29)27-15(23)14(26-13)17(30)28-18(24)25/h5-8H,1-4,9-10H2,(H2,23,27)(H4,24,25,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assay				J Med Chem 61: 8299-8320 (2018) Article DOI: 10.1021/acs.jmedchem.8b00838 BindingDB Entry DOI: 10.7270/Q2QF8WH4
					More data for this Ligand-Target Pair