BDBM50460674 CHEMBL4225398

SMILES: OC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21

InChI Key: InChIKey=LJRZFKMJTJVLFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50460674 (CHEMBL4225398) Show SMILES OC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C21H18BrClFNO2/c22-18-10-15(24)9-17-16-3-1-2-13(8-19(26)27)20(16)25(21(17)18)11-12-4-6-14(23)7-5-12/h4-7,9-10,13H,1-3,8,11H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 (unknown origin)				Bioorg Med Chem Lett 28: 1122-1126 (2018) Article DOI: 10.1016/j.bmcl.2018.01.039 BindingDB Entry DOI: 10.7270/Q2QV3Q4C
					More data for this Ligand-Target Pair