BDBM50460847 CHEMBL4228742

SMILES: FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)C2CCN(CC3CCCC3)CC2)c1

InChI Key: InChIKey=DEPSCOZETQUAAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-like protein 1 (Homo sapiens)	BDBM50460847 (CHEMBL4228742 | US11116757, No. A65) Show SMILES FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)C2CCN(CC3CCCC3)CC2)c1 Show InChI InChI=1S/C26H32F3N3O/c27-26(28,29)22-11-6-12-23(17-22)30-25(33)32(19-21-7-2-1-3-8-21)24-13-15-31(16-14-24)18-20-9-4-5-10-20/h1-3,6-8,11-12,17,20,24H,4-5,9-10,13-16,18-19H2,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...				J Med Chem 61: 2680-2693 (2018) Article DOI: 10.1021/acs.jmedchem.7b01277 BindingDB Entry DOI: 10.7270/Q29K4DVZ
					More data for this Ligand-Target Pair
DCN1-UBC12 (Homo sapiens)	BDBM50460847 (CHEMBL4228742 | US11116757, No. A65) Show SMILES FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)C2CCN(CC3CCCC3)CC2)c1 Show InChI InChI=1S/C26H32F3N3O/c27-26(28,29)22-11-6-12-23(17-22)30-25(33)32(19-21-7-2-1-3-8-21)24-13-15-31(16-14-24)18-20-9-4-5-10-20/h1-3,6-8,11-12,17,20,24H,4-5,9-10,13-16,18-19H2,(H,30,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DCN1-UBC12 (Homo sapiens)	BDBM50460847 (CHEMBL4228742 | US11116757, No. A65) Show SMILES FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)C2CCN(CC3CCCC3)CC2)c1 Show InChI InChI=1S/C26H32F3N3O/c27-26(28,29)22-11-6-12-23(17-22)30-25(33)32(19-21-7-2-1-3-8-21)24-13-15-31(16-14-24)18-20-9-4-5-10-20/h1-3,6-8,11-12,17,20,24H,4-5,9-10,13-16,18-19H2,(H,30,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair