null
SMILES: OC(=O)c1cnc(Cl)nc1Oc1cccc2ocnc12
InChI Key: InChIKey=GBOBEDOXAWSVIB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Homo sapiens (Human)) | BDBM50461114 (CHEMBL4228970) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences & Peking Union Medical College Curated by ChEMBL | Assay Description Inhibition of human N-terminal His6-tagged Pin1 PPIase activity expressed in Escherichia coli BL21 using Suc-Ala-Glu-cis-Pro-Phe-4-nitroanilide as su... | Bioorg Med Chem 26: 2186-2197 (2018) Article DOI: 10.1016/j.bmc.2018.03.024 BindingDB Entry DOI: 10.7270/Q2RN3BH0 | |||||||||||
More data for this Ligand-Target Pair |