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SMILES: Clc1ncc(-c2nnco2)c(Nc2ccccc2)n1

InChI Key: InChIKey=MBQXAWOAMIJTMJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461125   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1


(Homo sapiens (Human))		BDBM50461125
PNG
(CHEMBL4225874)
Show SMILES Clc1ncc(-c2nnco2)c(Nc2ccccc2)n1
Show InChI InChI=1S/C12H8ClN5O/c13-12-14-6-9(11-18-15-7-19-11)10(17-12)16-8-4-2-1-3-5-8/h1-7H,(H,14,16,17)
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MMDB

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PC cid
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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Medical Sciences & Peking Union Medical College

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Pin1 PPIase activity expressed in Escherichia coli BL21 using Suc-Ala-Glu-cis-Pro-Phe-4-nitroanilide as su...

Bioorg Med Chem 26: 2186-2197 (2018)


Article DOI: 10.1016/j.bmc.2018.03.024
BindingDB Entry DOI: 10.7270/Q2RN3BH0
More data for this
Ligand-Target Pair