BDBM50461279 CHEMBL4224750
SMILES: OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1
InChI Key: InChIKey=LVPRDAROHHDLOY-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM50461279 (CHEMBL4224750) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.71E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
IITB-Monash Research Academy Curated by ChEMBL | Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ... | Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B/Voltage-dependent calcium channel subunit alpha-2/delta-1/Voltage-dependent L-type calcium channel subunit beta-3 (Homo sapiens (Human)) | BDBM50461279 (CHEMBL4224750) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
IITB-Monash Research Academy Curated by ChEMBL | Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a... | Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253 | |||||||||||
More data for this Ligand-Target Pair |