null

SMILES: NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1

InChI Key: InChIKey=JGUWBIMENRLPBJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50462248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50462248 (CHEMBL4247158) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1 Show InChI InChI=1S/C14H11N5O4S/c15-24(22,23)10-6-4-9(5-7-10)19-13(11-3-1-2-8-16-11)12(14(20)21)17-18-19/h1-8H,(H,20,21)(H2,15,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	736	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of membrane bound human carbonic anhydrase 4 by stopped flow CO2 hydration assay				Eur J Med Chem 150: 678-686 (2018) Article DOI: 10.1016/j.ejmech.2018.03.030 BindingDB Entry DOI: 10.7270/Q2T43WR6
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50462248 (CHEMBL4247158) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1 Show InChI InChI=1S/C14H11N5O4S/c15-24(22,23)10-6-4-9(5-7-10)19-13(11-3-1-2-8-16-11)12(14(20)21)17-18-19/h1-8H,(H,20,21)(H2,15,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	808	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of cytosolic human carbonic anhydrase 2 by stopped flow CO2 hydration assay				Eur J Med Chem 150: 678-686 (2018) Article DOI: 10.1016/j.ejmech.2018.03.030 BindingDB Entry DOI: 10.7270/Q2T43WR6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50462248 (CHEMBL4247158) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1 Show InChI InChI=1S/C14H11N5O4S/c15-24(22,23)10-6-4-9(5-7-10)19-13(11-3-1-2-8-16-11)12(14(20)21)17-18-19/h1-8H,(H,20,21)(H2,15,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	881	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of cytosolic human carbonic anhydrase 1 by stopped flow CO2 hydration assay				Eur J Med Chem 150: 678-686 (2018) Article DOI: 10.1016/j.ejmech.2018.03.030 BindingDB Entry DOI: 10.7270/Q2T43WR6
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50462248 (CHEMBL4247158) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1 Show InChI InChI=1S/C14H11N5O4S/c15-24(22,23)10-6-4-9(5-7-10)19-13(11-3-1-2-8-16-11)12(14(20)21)17-18-19/h1-8H,(H,20,21)(H2,15,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50462248 (CHEMBL4247158) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(C(O)=O)c1-c1ccccn1 Show InChI InChI=1S/C14H11N5O4S/c15-24(22,23)10-6-4-9(5-7-10)19-13(11-3-1-2-8-16-11)12(14(20)21)17-18-19/h1-8H,(H,20,21)(H2,15,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of transmembrane human carbonic anhydrase 9 by stopped flow CO2 hydration assay				Eur J Med Chem 150: 678-686 (2018) Article DOI: 10.1016/j.ejmech.2018.03.030 BindingDB Entry DOI: 10.7270/Q2T43WR6
					More data for this Ligand-Target Pair