BDBM50462415 CHEMBL4250492

SMILES: N[C@@H](CCn1cc(nn1)-c1ccncc1)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=WKHKVNIKWXCMHW-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50462415 (CHEMBL4250492) Show SMILES N[C@@H](CCn1cc(nn1)-c1ccncc1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H16F3N5/c18-14-9-16(20)15(19)8-12(14)7-13(21)3-6-25-10-17(23-24-25)11-1-4-22-5-2-11/h1-2,4-5,8-10,13H,3,6-7,21H2/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50462415 (CHEMBL4250492) Show SMILES N[C@@H](CCn1cc(nn1)-c1ccncc1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H16F3N5/c18-14-9-16(20)15(19)8-12(14)7-13(21)3-6-25-10-17(23-24-25)11-1-4-22-5-2-11/h1-2,4-5,8-10,13H,3,6-7,21H2/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP4 using Gly-Pro-AMC as substrate after 1 hr by fluorescence assay				Eur J Med Chem 151: 145-157 (2018) Article DOI: 10.1016/j.ejmech.2018.03.041 BindingDB Entry DOI: 10.7270/Q2CZ39SV
					More data for this Ligand-Target Pair