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BDBM50462502 CHEMBL4248460

SMILES: Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1Cl

InChI Key: InChIKey=JAWNRLZTUAFYAS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462502   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aspartate aminotransferase, cytoplasmic


(Homo sapiens)		BDBM50462502
PNG
(CHEMBL4248460)
Show SMILES Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1Cl
Show InChI InChI=1S/C17H15Cl2N3O/c18-14-6-5-12(9-15(14)19)22-17(23)20-8-7-11-10-21-16-4-2-1-3-13(11)16/h1-6,9-10,21H,7-8H2,(H2,20,22,23)
PDB

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UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



California Institute for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay

Bioorg Med Chem Lett 28: 2675-2678 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.061
BindingDB Entry DOI: 10.7270/Q2MC92P6
More data for this
Ligand-Target Pair