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SMILES: Clc1nc(N2CCC(CC2)N2CCCCC2)c2ccn(Cc3ccccc3)c2n1

InChI Key: InChIKey=OFKLUJDWQGDFGL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462997   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50462997
PNG
(CHEMBL4239928)
Show SMILES Clc1nc(N2CCC(CC2)N2CCCCC2)c2ccn(Cc3ccccc3)c2n1
Show InChI InChI=1S/C23H28ClN5/c24-23-25-21(28-14-9-19(10-15-28)27-12-5-2-6-13-27)20-11-16-29(22(20)26-23)17-18-7-3-1-4-8-18/h1,3-4,7-8,11,16,19H,2,5-6,9-10,12-15,17H2
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 490n/an/an/an/an/an/an/an/a



Pontificia Universidad Cat£lica de Chile

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from human H3 receptor

Bioorg Med Chem Lett 28: 2890-2893 (2018)


Article DOI: 10.1016/j.bmcl.2018.07.023
BindingDB Entry DOI: 10.7270/Q2GH9MM2
More data for this
Ligand-Target Pair