null

SMILES: Cc1ccc(cc1)-n1nc(COC(=O)COc2cc(O)c3c(c2)oc(cc3=O)-c2ccccc2)cc1-c1cccc(C)c1

InChI Key: InChIKey=ICYPBWIWYWPPNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50463069 (CHEMBL4250212) Show SMILES Cc1ccc(cc1)-n1nc(COC(=O)COc2cc(O)c3c(c2)oc(cc3=O)-c2ccccc2)cc1-c1cccc(C)c1 Show InChI InChI=1S/C35H28N2O6/c1-22-11-13-27(14-12-22)37-29(25-10-6-7-23(2)15-25)16-26(36-37)20-42-34(40)21-41-28-17-30(38)35-31(39)19-32(43-33(35)18-28)24-8-4-3-5-9-24/h3-19,38H,20-21H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) using arachidonic acid as substrate pretreated for 10 mins followed by substrate addition and measured after 2 mi...				Bioorg Med Chem 26: 4264-4275 (2018) Article DOI: 10.1016/j.bmc.2018.07.022 BindingDB Entry DOI: 10.7270/Q2ZK5KBK
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50463069 (CHEMBL4250212) Show SMILES Cc1ccc(cc1)-n1nc(COC(=O)COc2cc(O)c3c(c2)oc(cc3=O)-c2ccccc2)cc1-c1cccc(C)c1 Show InChI InChI=1S/C35H28N2O6/c1-22-11-13-27(14-12-22)37-29(25-10-6-7-23(2)15-25)16-26(36-37)20-42-34(40)21-41-28-17-30(38)35-31(39)19-32(43-33(35)18-28)24-8-4-3-5-9-24/h3-19,38H,20-21H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of COX2 (unknown origin) using arachidonic acid as substrate pretreated for 10 mins followed by substrate addition and measured after 2 mi...				Bioorg Med Chem 26: 4264-4275 (2018) Article DOI: 10.1016/j.bmc.2018.07.022 BindingDB Entry DOI: 10.7270/Q2ZK5KBK
					More data for this Ligand-Target Pair