BDBM50463110 CHEMBL2136004

SMILES: Fc1ccc(cc1)N1CCN(CC(=O)Nc2ccccc2)CC1

InChI Key: InChIKey=FRSGRPJCNZGWDU-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein REV1 (Homo sapiens)	BDBM50463110 (CHEMBL2136004) Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2ccccc2)CC1 Show InChI InChI=1S/C18H20FN3O/c19-15-6-8-17(9-7-15)22-12-10-21(11-13-22)14-18(23)20-16-4-2-1-3-5-16/h1-9H,10-14H2,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	4.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair
DNA repair protein REV1 (Homo sapiens)	BDBM50463110 (CHEMBL2136004) Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2ccccc2)CC1 Show InChI InChI=1S/C18H20FN3O/c19-15-6-8-17(9-7-15)22-12-10-21(11-13-22)14-18(23)20-16-4-2-1-3-5-16/h1-9H,10-14H2,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair
DNA repair protein REV1 (Homo sapiens)	BDBM50463110 (CHEMBL2136004) Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2ccccc2)CC1 Show InChI InChI=1S/C18H20FN3O/c19-15-6-8-17(9-7-15)22-12-10-21(11-13-22)14-18(23)20-16-4-2-1-3-5-16/h1-9H,10-14H2,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.22E+4	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...				Bioorg Med Chem 26: 4301-4309 (2018) Article DOI: 10.1016/j.bmc.2018.07.029 BindingDB Entry DOI: 10.7270/Q2K93B5H
					More data for this Ligand-Target Pair