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BDBM50463339 CHEMBL4250839

SMILES: Cc1cc(cc(C)c1NC(=O)CC(C)(C)C)N1CCCCc2cc(Cl)ccc12

InChI Key: InChIKey=IFDYNXGKQRLIFY-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily KQT member 2


(Homo sapiens (Human))		BDBM50463339
PNG
(CHEMBL4250839)
Show SMILES Cc1cc(cc(C)c1NC(=O)CC(C)(C)C)N1CCCCc2cc(Cl)ccc12
Show InChI InChI=1S/C24H31ClN2O/c1-16-12-20(13-17(2)23(16)26-22(28)15-24(3,4)5)27-11-7-6-8-18-14-19(25)9-10-21(18)27/h9-10,12-14H,6-8,11,15H2,1-5H3,(H,26,28)
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n/an/an/an/a 140n/an/an/an/a



Nanjing University of Technology

Curated by ChEMBL


Assay Description
Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assay

Bioorg Med Chem Lett 28: 3004-3008 (2018)


Article DOI: 10.1016/j.bmcl.2018.05.019
BindingDB Entry DOI: 10.7270/Q2H997WB
More data for this
Ligand-Target Pair