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SMILES: CC(C)(O)c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=BFSZGLRGQFVSKC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463434   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50463434
PNG
(CHEMBL3781118)
Show SMILES CC(C)(O)c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C17H18F3NO3S/c1-16(2,22)13-8-10-14(11-9-13)21(12-17(18,19)20)25(23,24)15-6-4-3-5-7-15/h3-11,22H,12H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of human RORgamma1 expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay

Bioorg Med Chem 26: 4493-4501 (2018)


Article DOI: 10.1016/j.bmc.2018.07.038
BindingDB Entry DOI: 10.7270/Q2QV3Q5T
More data for this
Ligand-Target Pair