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SMILES: [#6]-[#7](-c1ccc(cc1)[Si;v4]([#6])([#6])[#8])S(=O)(=O)c1ccccc1

InChI Key: InChIKey=DMQWCSBVIYWTGT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463441   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor subfamily 1 group I member 2


(Homo sapiens (Human))		BDBM50463441
PNG
(CHEMBL4243271)
Show SMILES [#6]-[#7](-c1ccc(cc1)[Si;v4]([#6])([#6])[#8])S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C15H19NO3SSi/c1-16(20(17,18)14-7-5-4-6-8-14)13-9-11-15(12-10-13)21(2,3)19/h4-12,19H,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.40E+3n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at VP16-fused human PXR expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay

Bioorg Med Chem 26: 4493-4501 (2018)


Article DOI: 10.1016/j.bmc.2018.07.038
BindingDB Entry DOI: 10.7270/Q2QV3Q5T
More data for this
Ligand-Target Pair