BDBM50463514 CHEMBL4240335

SMILES: CCc1n[nH]cc1-c1ccc2nc[nH]c(=O)c2c1

InChI Key: InChIKey=XUHMCCMZFGPLIV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activin receptor type-1 (Homo sapiens (Human))	BDBM50463514 (CHEMBL4240335) Show SMILES CCc1n[nH]cc1-c1ccc2nc[nH]c(=O)c2c1 Show InChI InChI=1S/C13H12N4O/c1-2-11-10(6-16-17-11)8-3-4-12-9(5-8)13(18)15-7-14-12/h3-7H,2H2,1H3,(H,16,17)(H,14,15,18)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human ALK2 catalytic domain (145 to 509 residues) expressed in Baculovirus expression system by FRET-based Lanth...				J Med Chem 61: 7261-7272 (2018) Article DOI: 10.1021/acs.jmedchem.8b00782 BindingDB Entry DOI: 10.7270/Q2K64MRS
					More data for this Ligand-Target Pair