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SMILES: O=c1n(cnc2ccc(cc12)-c1ccnc2ccccc12)C1CCCCC1

InChI Key: InChIKey=RABDRCWAVFBAEA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463518   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Activin receptor type-1


(Homo sapiens (Human))		BDBM50463518
PNG
(CHEMBL4248621)
Show SMILES O=c1n(cnc2ccc(cc12)-c1ccnc2ccccc12)C1CCCCC1
Show InChI InChI=1S/C23H21N3O/c27-23-20-14-16(18-12-13-24-21-9-5-4-8-19(18)21)10-11-22(20)25-15-26(23)17-6-2-1-3-7-17/h4-5,8-15,17H,1-3,6-7H2
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.53E+3n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged human ALK2 catalytic domain (145 to 509 residues) expressed in Baculovirus expression system by FRET-based Lanth...

J Med Chem 61: 7261-7272 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00782
BindingDB Entry DOI: 10.7270/Q2K64MRS
More data for this
Ligand-Target Pair