BDBM50463530 CHEMBL4237276

SMILES: O=c1n(CCCN2CCOCC2)cnc2ccc(cc12)-c1ccnc2ccccc12

InChI Key: InChIKey=YFMTWBBWQYWRMJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activin receptor type-1 (Homo sapiens (Human))	BDBM50463530 (CHEMBL4237276) Show SMILES O=c1n(CCCN2CCOCC2)cnc2ccc(cc12)-c1ccnc2ccccc12 Show InChI InChI=1S/C24H24N4O2/c29-24-21-16-18(19-8-9-25-22-5-2-1-4-20(19)22)6-7-23(21)26-17-28(24)11-3-10-27-12-14-30-15-13-27/h1-2,4-9,16-17H,3,10-15H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human ALK2 catalytic domain (145 to 509 residues) expressed in Baculovirus expression system by FRET-based Lanth...				J Med Chem 61: 7261-7272 (2018) Article DOI: 10.1021/acs.jmedchem.8b00782 BindingDB Entry DOI: 10.7270/Q2K64MRS
					More data for this Ligand-Target Pair