BDBM50463866 CHEMBL4247847

SMILES: C[C@H](NC(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)c1ncccc1F)C(F)(F)F

InChI Key: InChIKey=VKGPLEBLUUTJQS-ZANVPECISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463866   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM50463866 (CHEMBL4247847) Show SMILES C[C@H](NC(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)c1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C17H14F7N3O/c1-9(16(19,20)21)26-15(28)27-13(14-12(18)3-2-8-25-14)10-4-6-11(7-5-10)17(22,23)24/h2-9,13H,1H3,(H2,26,27,28)/t9-,13-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mus musculus)	BDBM50463866 (CHEMBL4247847) Show SMILES C[C@H](NC(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)c1ncccc1F)C(F)(F)F |r| Show InChI InChI=1S/C17H14F7N3O/c1-9(16(19,20)21)26-15(28)27-13(14-12(18)3-2-8-25-14)10-4-6-11(7-5-10)17(22,23)24/h2-9,13H,1H3,(H2,26,27,28)/t9-,13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair