BDBM50464133 CHEMBL4238181

SMILES: CO[C@@H]1CNC[C@H](OC)[C@H]1Nc1nccc2cc(C)c(=O)[nH]c12

InChI Key: InChIKey=XVRXTHYPYWDQSR-IMRBUKKESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50464133 (CHEMBL4238181) Show SMILES CO[C@@H]1CNC[C@H](OC)[C@H]1Nc1nccc2cc(C)c(=O)[nH]c12 |r| Show InChI InChI=1S/C16H22N4O3/c1-9-6-10-4-5-18-15(13(10)20-16(9)21)19-14-11(22-2)7-17-8-12(14)23-3/h4-6,11-12,14,17H,7-8H2,1-3H3,(H,18,19)(H,20,21)/t11-,12+,14+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of 6His-tagged Thr-BRD4 (BD1) (1 to 477 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins in presence of bi...				J Med Chem 61: 8321-8336 (2018) Article DOI: 10.1021/acs.jmedchem.8b00862 BindingDB Entry DOI: 10.7270/Q2125WBR
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50464133 (CHEMBL4238181) Show SMILES CO[C@@H]1CNC[C@H](OC)[C@H]1Nc1nccc2cc(C)c(=O)[nH]c12 |r| Show InChI InChI=1S/C16H22N4O3/c1-9-6-10-4-5-18-15(13(10)20-16(9)21)19-14-11(22-2)7-17-8-12(14)23-3/h4-6,11-12,14,17H,7-8H2,1-3H3,(H,18,19)(H,20,21)/t11-,12+,14+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-6His-tagged TEV-fused ATAD2 (981 to 1121 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mi...				J Med Chem 61: 8321-8336 (2018) Article DOI: 10.1021/acs.jmedchem.8b00862 BindingDB Entry DOI: 10.7270/Q2125WBR
					More data for this Ligand-Target Pair