BDBM50464476 CHEMBL4285438

SMILES: COc1ccc(cc1)C1=C(O)C(=O)c2ccccc2C1=O

InChI Key: InChIKey=LLMWUKJCIBAIJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Mus musculus)	BDBM50464476 (CHEMBL4285438) Show SMILES COc1ccc(cc1)C1=C(O)C(=O)c2ccccc2C1=O |c:9| Show InChI InChI=1S/C17H12O4/c1-21-11-8-6-10(7-9-11)14-15(18)12-4-2-3-5-13(12)16(19)17(14)20/h2-9,20H,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Oswaldo Cruz Curated by ChEMBL					Assay Description Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated...				Eur J Med Chem 143: 1361-1372 (2018) Article DOI: 10.1016/j.ejmech.2017.10.033 BindingDB Entry DOI: 10.7270/Q2KS6V7K
					More data for this Ligand-Target Pair