BDBM50464542 CHEMBL4280004

SMILES: Fc1ccc(cc1)-n1c2ncccc2cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1=O

InChI Key: InChIKey=CQCVNKBXWWKFDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50464542 (CHEMBL4280004) Show SMILES Fc1ccc(cc1)-n1c2ncccc2cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1=O Show InChI InChI=1S/C28H18FN5O3/c29-18-3-7-20(8-4-18)34-26-17(2-1-13-32-26)16-23(28(34)36)27(35)33-19-5-9-21(10-6-19)37-24-12-15-31-25-22(24)11-14-30-25/h1-16H,(H,30,31)(H,33,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMET (unknown origin) using poly(Glu,Tyr) 4:1 substrate after 30 mins by HTFR analysis				Eur J Med Chem 143: 266-275 (2018) Article DOI: 10.1016/j.ejmech.2017.11.034 BindingDB Entry DOI: 10.7270/Q2JW8HJZ
					More data for this Ligand-Target Pair