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SMILES: Fc1ccc(CN[C@H]2C[C@@H]2c2ccccc2)cc1F

InChI Key: InChIKey=GSWRQXVOLJJEEL-CJNGLKHVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50464668
PNG
(CHEMBL4285786)
Show SMILES Fc1ccc(CN[C@H]2C[C@@H]2c2ccccc2)cc1F |r|
Show InChI InChI=1S/C16H15F2N/c17-14-7-6-11(8-15(14)18)10-19-16-9-13(16)12-4-2-1-3-5-12/h1-8,13,16,19H,9-10H2/t13-,16+/m1/s1
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n/an/a 100n/an/an/an/an/an/a



University of Freiburg

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) expressed in baculovirus infected sf9 cells preincubated for 15 mins followed by H...

Eur J Med Chem 144: 52-67 (2018)


Article DOI: 10.1016/j.ejmech.2017.12.001
BindingDB Entry DOI: 10.7270/Q20V8GGB
More data for this
Ligand-Target Pair