BDBM50464741 CHEMBL4294808

SMILES: FC(F)(F)c1cccc(c1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1

InChI Key: InChIKey=FONGRVJAXDBMGV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM50464741 (CHEMBL4294808) Show SMILES FC(F)(F)c1cccc(c1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1 Show InChI InChI=1S/C13H5F6N3OS/c14-12(15,16)7-3-1-2-6(4-7)10-21-22-9(23)5-8(13(17,18)19)20-11(22)24-10/h1-5H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human IAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by ...				Eur J Med Chem 144: 116-127 (2018) Article DOI: 10.1016/j.ejmech.2017.11.068 BindingDB Entry DOI: 10.7270/Q2W66PDP
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50464741 (CHEMBL4294808) Show SMILES FC(F)(F)c1cccc(c1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1 Show InChI InChI=1S/C13H5F6N3OS/c14-12(15,16)7-3-1-2-6(4-7)10-21-22-9(23)5-8(13(17,18)19)20-11(22)24-10/h1-5H	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Rostock Curated by ChEMBL					Assay Description Inhibition of human TNAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by...				Eur J Med Chem 144: 116-127 (2018) Article DOI: 10.1016/j.ejmech.2017.11.068 BindingDB Entry DOI: 10.7270/Q2W66PDP
					More data for this Ligand-Target Pair