BDBM50465225 CHEMBL4292475::US10766903, Example 22

SMILES: C[C@H](CC(=O)N1CCC(O)(Cn2cnc3c(C#C)n(C)nc3c2=O)CC1)c1ccccc1

InChI Key: InChIKey=ABRGPVVIVBNDCQ-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465225 (CHEMBL4292475 | US10766903, Example 22) Show SMILES C[C@H](CC(=O)N1CCC(O)(Cn2cnc3c(C#C)n(C)nc3c2=O)CC1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-4-19-21-22(26-27(19)3)23(31)29(16-25-21)15-24(32)10-12-28(13-11-24)20(30)14-17(2)18-8-6-5-7-9-18/h1,5-9,16-17,32H,10-15H2,2-3H3/t17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
ALMAC DISCOVERY LIMITED US Patent					Assay Description USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...				US Patent US10766903 (2020)
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465225 (CHEMBL4292475 | US10766903, Example 22) Show SMILES C[C@H](CC(=O)N1CCC(O)(Cn2cnc3c(C#C)n(C)nc3c2=O)CC1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O3/c1-4-19-21-22(26-27(19)3)23(31)29(16-25-21)15-24(32)10-12-28(13-11-24)20(30)14-17(2)18-8-6-5-7-9-18/h1,5-9,16-17,32H,10-15H2,2-3H3/t17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Almac Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) by biochemical assay				ACS Med Chem Lett 9: 238-243 (2018) Article DOI: 10.1021/acsmedchemlett.7b00512 BindingDB Entry DOI: 10.7270/Q2Q81GRX
					More data for this Ligand-Target Pair