BDBM50465226 CHEMBL4292642::US10766903, Example 90

SMILES: CSc1nc2ncn(CC3(O)CCN(CC3)C(=O)CCc3ccccc3)c(=O)c2s1

InChI Key: InChIKey=ISRBTKQFJBHJPU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465226 (CHEMBL4292642 | US10766903, Example 90) Show SMILES CSc1nc2ncn(CC3(O)CCN(CC3)C(=O)CCc3ccccc3)c(=O)c2s1 Show InChI InChI=1S/C21H24N4O3S2/c1-29-20-23-18-17(30-20)19(27)25(14-22-18)13-21(28)9-11-24(12-10-21)16(26)8-7-15-5-3-2-4-6-15/h2-6,14,28H,7-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
ALMAC DISCOVERY LIMITED US Patent					Assay Description USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...				US Patent US10766903 (2020)
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465226 (CHEMBL4292642 | US10766903, Example 90) Show SMILES CSc1nc2ncn(CC3(O)CCN(CC3)C(=O)CCc3ccccc3)c(=O)c2s1 Show InChI InChI=1S/C21H24N4O3S2/c1-29-20-23-18-17(30-20)19(27)25(14-22-18)13-21(28)9-11-24(12-10-21)16(26)8-7-15-5-3-2-4-6-15/h2-6,14,28H,7-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Almac Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) by biochemical assay				ACS Med Chem Lett 9: 238-243 (2018) Article DOI: 10.1021/acsmedchemlett.7b00512 BindingDB Entry DOI: 10.7270/Q2Q81GRX
					More data for this Ligand-Target Pair