BDBM50465228 CHEMBL4287739

SMILES: C[C@H](CC(=O)N1CCC(O)(Cn2cnc3c(Br)csc3c2=O)CC1)c1ccccc1

InChI Key: InChIKey=NRRXSEFLOFZNSO-OAHLLOKOSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465228 (CHEMBL4287739) Show SMILES C[C@H](CC(=O)N1CCC(O)(Cn2cnc3c(Br)csc3c2=O)CC1)c1ccccc1 |r| Show InChI InChI=1S/C22H24BrN3O3S/c1-15(16-5-3-2-4-6-16)11-18(27)25-9-7-22(29,8-10-25)13-26-14-24-19-17(23)12-30-20(19)21(26)28/h2-6,12,14-15,29H,7-11,13H2,1H3/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Almac Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) by biochemical assay				ACS Med Chem Lett 9: 238-243 (2018) Article DOI: 10.1021/acsmedchemlett.7b00512 BindingDB Entry DOI: 10.7270/Q2Q81GRX
					More data for this Ligand-Target Pair				3D Structure (crystal)