BDBM50465345 18-OXOFERRUGINOL::18-Oxoferruginol
SMILES: [H][C@@]12CCc3cc(C(C)C)c(O)cc3[C@@]1(C)CCC[C@@]2(C)C=O
InChI Key: InChIKey=BYISLTMARMJFNI-SLFFLAALSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine--tRNA ligase (Homo sapiens (Human)) | BDBM50465345 (18-OXOFERRUGINOL | 18-Oxoferruginol | acs.jmedchem...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Yunnan University Curated by ChEMBL | Assay Description Inhibition of SYK (unknown origin) by mobility shift assay | J Nat Prod 81: 998-1006 (2018) Article DOI: 10.1021/acs.jnatprod.7b01082 BindingDB Entry DOI: 10.7270/Q2P84FK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...) | BDBM50465345 (18-OXOFERRUGINOL | 18-Oxoferruginol | acs.jmedchem...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.63E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...) | BDBM50465345 (18-OXOFERRUGINOL | 18-Oxoferruginol | acs.jmedchem...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.63E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of SARS coronavirus 3C-like protease after 60 mins by FRET assay | Bioorg Med Chem 18: 7940-7 (2010) Article DOI: 10.1016/j.bmc.2010.09.035 BindingDB Entry DOI: 10.7270/Q2MG7SBP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM50465345 (18-OXOFERRUGINOL | 18-Oxoferruginol | acs.jmedchem...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Yunnan University Curated by ChEMBL | Assay Description Inhibition of JAK3 (unknown origin) by mobility shift assay | J Nat Prod 81: 998-1006 (2018) Article DOI: 10.1021/acs.jnatprod.7b01082 BindingDB Entry DOI: 10.7270/Q2P84FK3 | |||||||||||
More data for this Ligand-Target Pair |