BDBM50465570 CHEMBL4292147

SMILES: COc1ccc(cc1)C(=O)NCc1cccc(c1)-c1cn2CCCc2n1

InChI Key: InChIKey=WOHXAOWQRBNCMD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50465570 (CHEMBL4292147) Show SMILES COc1ccc(cc1)C(=O)NCc1cccc(c1)-c1cn2CCCc2n1 Show InChI InChI=1S/C21H21N3O2/c1-26-18-9-7-16(8-10-18)21(25)22-13-15-4-2-5-17(12-15)19-14-24-11-3-6-20(24)23-19/h2,4-5,7-10,12,14H,3,6,11,13H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...				J Med Chem 61: 5623-5642 (2018) Article DOI: 10.1021/acs.jmedchem.8b00375 BindingDB Entry DOI: 10.7270/Q2KD21KT
					More data for this Ligand-Target Pair