BDBM50465571 CHEMBL4278066

SMILES: O=C(Cc1ccccc1)NCc1cccc(c1)-c1cn2CCCc2n1

InChI Key: InChIKey=GKIAAVNOBCFHHP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50465571 (CHEMBL4278066) Show SMILES O=C(Cc1ccccc1)NCc1cccc(c1)-c1cn2CCCc2n1 Show InChI InChI=1S/C21H21N3O/c25-21(13-16-6-2-1-3-7-16)22-14-17-8-4-9-18(12-17)19-15-24-11-5-10-20(24)23-19/h1-4,6-9,12,15H,5,10-11,13-14H2,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...				J Med Chem 61: 5623-5642 (2018) Article DOI: 10.1021/acs.jmedchem.8b00375 BindingDB Entry DOI: 10.7270/Q2KD21KT
					More data for this Ligand-Target Pair