BDBM50465580 CHEMBL4276791

SMILES: COc1cccc(c1)C(=O)NCc1cc(ccc1N(C)C)-c1cn2CCCc2n1

InChI Key: InChIKey=NYCQMHOKYBUOQV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50465580 (CHEMBL4276791) Show SMILES COc1cccc(c1)C(=O)NCc1cc(ccc1N(C)C)-c1cn2CCCc2n1 Show InChI InChI=1S/C23H26N4O2/c1-26(2)21-10-9-16(20-15-27-11-5-8-22(27)25-20)12-18(21)14-24-23(28)17-6-4-7-19(13-17)29-3/h4,6-7,9-10,12-13,15H,5,8,11,14H2,1-3H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to N-terminal 6x-His-SUMO tagged WDR5 delta23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli BL...				J Med Chem 61: 5623-5642 (2018) Article DOI: 10.1021/acs.jmedchem.8b00375 BindingDB Entry DOI: 10.7270/Q2KD21KT
					More data for this Ligand-Target Pair