BDBM50465609 CHEMBL4277150

SMILES: Cn1cc(CCN(Cc2ccccc2)Cc2ccccc2)c2ccccc12

InChI Key: InChIKey=LRHCLVBJKHJVFW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (TRPM8) (Rattus norvegicus (Rat))	BDBM50465609 (CHEMBL4277150) Show SMILES Cn1cc(CCN(Cc2ccccc2)Cc2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H26N2/c1-26-20-23(24-14-8-9-15-25(24)26)16-17-27(18-21-10-4-2-5-11-21)19-22-12-6-3-7-13-22/h2-15,20H,16-19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...				J Med Chem 61: 6140-6152 (2018) Article DOI: 10.1021/acs.jmedchem.8b00545 BindingDB Entry DOI: 10.7270/Q2FN18V3
					More data for this Ligand-Target Pair