BDBM50465937 CHEMBL4287192

SMILES: Cc1cc(Oc2nccc3occc23)ccc1-c1cncc2ncnn12

InChI Key: InChIKey=OUGRRYAUMLQMJR-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50465937 (CHEMBL4287192) Show SMILES Cc1cc(Oc2nccc3occc23)ccc1-c1cncc2ncnn12 Show InChI InChI=1S/C19H13N5O2/c1-12-8-13(26-19-15-5-7-25-17(15)4-6-21-19)2-3-14(12)16-9-20-10-18-22-11-23-24(16)18/h2-11H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH23390 from human dopamine D1 receptor expressed in LTK cell membranes after 30 mins by liquid scintillation counting				J Med Chem 61: 11384-11397 (2018) Article DOI: 10.1021/acs.jmedchem.8b01622 BindingDB Entry DOI: 10.7270/Q20G3NT6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50465937 (CHEMBL4287192) Show SMILES Cc1cc(Oc2nccc3occc23)ccc1-c1cncc2ncnn12 Show InChI InChI=1S/C19H13N5O2/c1-12-8-13(26-19-15-5-7-25-17(15)4-6-21-19)2-3-14(12)16-9-20-10-18-22-11-23-24(16)18/h2-11H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human dopamine D1 receptor expressed in HEK293T cells assessed as induction of cAMP levels after 30 mins by HTRF assay				J Med Chem 61: 11384-11397 (2018) Article DOI: 10.1021/acs.jmedchem.8b01622 BindingDB Entry DOI: 10.7270/Q20G3NT6
					More data for this Ligand-Target Pair