BDBM50466256 CHEMBL4284925

SMILES: CN1CCN(CC1)c1nc(NCc2cccc(Cl)c2)c2cc(ccc2n1)-c1c(C)noc1C

InChI Key: InChIKey=JRHBUWGROINRFO-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50466256 (CHEMBL4284925) Show SMILES CN1CCN(CC1)c1nc(NCc2cccc(Cl)c2)c2cc(ccc2n1)-c1c(C)noc1C Show InChI InChI=1S/C25H27ClN6O/c1-16-23(17(2)33-30-16)19-7-8-22-21(14-19)24(27-15-18-5-4-6-20(26)13-18)29-25(28-22)32-11-9-31(3)10-12-32/h4-8,13-14H,9-12,15H2,1-3H3,(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...				Bioorg Med Chem Lett 28: 3483-3488 (2018) Article DOI: 10.1016/j.bmcl.2018.08.039 BindingDB Entry DOI: 10.7270/Q28S4SKP
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