BDBM50466261 CHEMBL4279367

SMILES: Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)N1CCN(CC1)C(=O)CO

InChI Key: InChIKey=LBPMZEBBXUOHMJ-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50466261 (CHEMBL4279367) Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)N1CCN(CC1)C(=O)CO Show InChI InChI=1S/C26H27ClN6O3/c1-16-24(17(2)36-31-16)19-6-7-22-21(13-19)25(28-14-18-4-3-5-20(27)12-18)30-26(29-22)33-10-8-32(9-11-33)23(35)15-34/h3-7,12-13,34H,8-11,14-15H2,1-2H3,(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...				Bioorg Med Chem Lett 28: 3483-3488 (2018) Article DOI: 10.1016/j.bmcl.2018.08.039 BindingDB Entry DOI: 10.7270/Q28S4SKP
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