BDBM50466262 CHEMBL4294517

SMILES: Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)-c1ccc(CO)nc1

InChI Key: InChIKey=KKIGYQMLDYXTCJ-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50466262 (CHEMBL4294517) Show SMILES Cc1noc(C)c1-c1ccc2nc(nc(NCc3cccc(Cl)c3)c2c1)-c1ccc(CO)nc1 Show InChI InChI=1S/C26H22ClN5O2/c1-15-24(16(2)34-32-15)18-7-9-23-22(11-18)26(29-12-17-4-3-5-20(27)10-17)31-25(30-23)19-6-8-21(14-33)28-13-19/h3-11,13,33H,12,14H2,1-2H3,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...				Bioorg Med Chem Lett 28: 3483-3488 (2018) Article DOI: 10.1016/j.bmcl.2018.08.039 BindingDB Entry DOI: 10.7270/Q28S4SKP
					More data for this Ligand-Target Pair