BDBM50466277 CHEMBL4281384

SMILES: CN(C)CCN1CCN(CC1)c1nc(NCc2cccs2)c2cc(ccc2n1)-c1c(C)noc1C

InChI Key: InChIKey=WFKUQDVLOFAHKR-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50466277 (CHEMBL4281384) Show SMILES CN(C)CCN1CCN(CC1)c1nc(NCc2cccs2)c2cc(ccc2n1)-c1c(C)noc1C Show InChI InChI=1S/C26H33N7OS/c1-18-24(19(2)34-30-18)20-7-8-23-22(16-20)25(27-17-21-6-5-15-35-21)29-26(28-23)33-13-11-32(12-14-33)10-9-31(3)4/h5-8,15-16H,9-14,17H2,1-4H3,(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...				Bioorg Med Chem Lett 28: 3483-3488 (2018) Article DOI: 10.1016/j.bmcl.2018.08.039 BindingDB Entry DOI: 10.7270/Q28S4SKP
					More data for this Ligand-Target Pair