BDBM50466284 CHEMBL4281025

SMILES: CN(C)CCN1CCN(CC1)c1nc(NCc2cccc(Cl)c2)c2ccc(cc2n1)-c1c(C)noc1C

InChI Key: InChIKey=CFYRYKWYJZVGTA-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50466284 (CHEMBL4281025) Show SMILES CN(C)CCN1CCN(CC1)c1nc(NCc2cccc(Cl)c2)c2ccc(cc2n1)-c1c(C)noc1C Show InChI InChI=1S/C28H34ClN7O/c1-19-26(20(2)37-33-19)22-8-9-24-25(17-22)31-28(36-14-12-35(13-15-36)11-10-34(3)4)32-27(24)30-18-21-6-5-7-23(29)16-21/h5-9,16-17H,10-15,18H2,1-4H3,(H,30,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of biotinylated acetylated peptide from recombinant human partial length BRD4 long isoform bromodomain 1/2 (N44 to E460 residues) expres...				Bioorg Med Chem Lett 28: 3483-3488 (2018) Article DOI: 10.1016/j.bmcl.2018.08.039 BindingDB Entry DOI: 10.7270/Q28S4SKP
					More data for this Ligand-Target Pair