BDBM50466392 CHEMBL4285448

SMILES: CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1

InChI Key: InChIKey=GZECANYKHKCEFF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50466392 (CHEMBL4285448) Show SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1 Show InChI InChI=1S/C27H21F2N5O3/c1-15(2)24-32-23-22(11-12-30-25(23)33-24)37-21-10-7-17(14-20(21)29)31-26(35)19-4-3-13-34(27(19)36)18-8-5-16(28)6-9-18/h3-15H,1-2H3,(H,31,35)(H,30,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
PSL Research University Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...				Bioorg Med Chem 26: 5510-5530 (2018) Article DOI: 10.1016/j.bmc.2018.09.031 BindingDB Entry DOI: 10.7270/Q27S7RGR
					More data for this Ligand-Target Pair