BDBM50466472 CHEMBL4289476
SMILES: [H][C@]1(OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)Cn1cc(C[C@H](N)C(=O)N[C@H](CCC(O)=O)C(N)=O)nn1
InChI Key: InChIKey=DRCUEAFGNLXWSO-DCPQRGJOSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sialidase 2 (Homo sapiens (Human)) | BDBM50466472 (CHEMBL4289476) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of recombinant human cytosolic sialidase NEU2 using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sialidase A (Streptococcus pneumoniae) | BDBM50466472 (CHEMBL4289476) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sialidase B (Streptococcus pneumoniae) | BDBM50466472 (CHEMBL4289476) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of Streptococcus pneumoniae sialidase NanC using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sialidase (Clostridium perfringens) | BDBM50466472 (CHEMBL4289476) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of Clostridium perfringens sialidase using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sialidase (Vibrio cholerae) | BDBM50466472 (CHEMBL4289476) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of Vibrio cholerae sialidase using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase B (NanB) (Streptococcus pneumoniae) | BDBM50466472 (CHEMBL4289476) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-Davis Curated by ChEMBL | Assay Description Inhibition of Streptococcus pneumoniae NanB using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assay | Bioorg Med Chem 26: 5751-5757 (2018) Article DOI: 10.1016/j.bmc.2018.10.028 BindingDB Entry DOI: 10.7270/Q2BK1G2N | |||||||||||
More data for this Ligand-Target Pair |