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SMILES: [I-].C(CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)CCOc1ccc(\C=C\c2ccccc2)cc1

InChI Key: InChIKey=PQRVKQPJBRFUIN-OCEACIFDSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466603   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50466603
PNG
(CHEMBL4277852)
Show SMILES [I-].C(CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)CCOc1ccc(\C=C\c2ccccc2)cc1
Show InChI InChI=1S/C38H38OP/c1(15-31-39-35-29-27-34(28-30-35)26-25-33-17-7-3-8-18-33)2-16-32-40(36-19-9-4-10-20-36,37-21-11-5-12-22-37)38-23-13-6-14-24-38/h3-14,17-30H,1-2,15-16,31-32H2/q+1/b26-25+
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 559n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Milano

Curated by ChEMBL


Assay Description
Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysis

J Med Chem 61: 10531-10544 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01052
BindingDB Entry DOI: 10.7270/Q2PV6P2W
More data for this
Ligand-Target Pair