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SMILES: [I-].C(CCCOc1ccc(\C=C\c2ccccc2)cc1)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=LUOTXSWNUKDJRN-CYYJNZCTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466615   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50466615
PNG
(CHEMBL4291927)
Show SMILES [I-].C(CCCOc1ccc(\C=C\c2ccccc2)cc1)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C39H40OP/c1(2-16-32-40-36-30-28-35(29-31-36)27-26-34-18-8-4-9-19-34)3-17-33-41(37-20-10-5-11-21-37,38-22-12-6-13-23-38)39-24-14-7-15-25-39/h4-15,18-31H,1-3,16-17,32-33H2/q+1/b27-26+
PDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 617n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Milano

Curated by ChEMBL


Assay Description
Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysis

J Med Chem 61: 10531-10544 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01052
BindingDB Entry DOI: 10.7270/Q2PV6P2W
More data for this
Ligand-Target Pair