BDBM50466640 CHEMBL4282189

SMILES: OC(=O)Cc1cccc(NC(=O)c2ccc(NC(=O)Nc3ccc(cc3)C(=O)Nc3cccc(CC(O)=O)c3)cc2)c1

InChI Key: InChIKey=JKUKNKLZICIRPH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heparanase (Homo sapiens (Human))	BDBM50466640 (CHEMBL4282189) Show SMILES OC(=O)Cc1cccc(NC(=O)c2ccc(NC(=O)Nc3ccc(cc3)C(=O)Nc3cccc(CC(O)=O)c3)cc2)c1 Show InChI InChI=1S/C31H26N4O7/c36-27(37)17-19-3-1-5-25(15-19)32-29(40)21-7-11-23(12-8-21)34-31(42)35-24-13-9-22(10-14-24)30(41)33-26-6-2-4-20(16-26)18-28(38)39/h1-16H,17-18H2,(H,32,40)(H,33,41)(H,36,37)(H,38,39)(H2,34,35,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assay				J Med Chem 61: 10834-10859 (2018) Article DOI: 10.1021/acs.jmedchem.8b01497 BindingDB Entry DOI: 10.7270/Q29K4DWD
					More data for this Ligand-Target Pair