BDBM50467133 CHEMBL4280574

SMILES: CCCCc1nc(C)c(CC(=S)N2[C@H](C)CC[C@H]2C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=HSTZZTBXVAHGDW-NHCUHLMSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50467133 (CHEMBL4280574) Show SMILES CCCCc1nc(C)c(CC(=S)N2[C@H](C)CC[C@H]2C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1 |r| Show InChI InChI=1S/C32H37N5O3S/c1-5-6-11-28-33-22(4)27(18-29(41)37-20(2)12-13-21(37)3)31(38)36(28)19-23-14-16-24(17-15-23)25-9-7-8-10-26(25)30-34-32(39)40-35-30/h7-10,14-17,20-21H,5-6,11-13,18-19H2,1-4H3,(H,34,35,39)/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Boryung Pharmaceuticals Co. Ltd. Curated by ChEMBL					Assay Description Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay				Bioorg Med Chem Lett 28: 3155-3160 (2018) Article DOI: 10.1016/j.bmcl.2018.08.036 BindingDB Entry DOI: 10.7270/Q2X63QMZ
					More data for this Ligand-Target Pair