BDBM50467134 CHEMBL4284403

SMILES: CCCCc1nc(C)c(CC(=S)N2Cc3ccccc3C2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=NMQSYHHTIOJROL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50467134 (CHEMBL4284403) Show SMILES CCCCc1nc(C)c(CC(=S)N2Cc3ccccc3C2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1 Show InChI InChI=1S/C34H33N5O3S/c1-3-4-13-30-35-22(2)29(18-31(43)38-20-25-9-5-6-10-26(25)21-38)33(40)39(30)19-23-14-16-24(17-15-23)27-11-7-8-12-28(27)32-36-34(41)42-37-32/h5-12,14-17H,3-4,13,18-21H2,1-2H3,(H,36,37,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Boryung Pharmaceuticals Co. Ltd. Curated by ChEMBL					Assay Description Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay				Bioorg Med Chem Lett 28: 3155-3160 (2018) Article DOI: 10.1016/j.bmcl.2018.08.036 BindingDB Entry DOI: 10.7270/Q2X63QMZ
					More data for this Ligand-Target Pair