BDBM50467137 CHEMBL4294618

SMILES: CCCCc1nc(C)c(CC(=S)N2CCCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=ZHLHYLQRZPRNHF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50467137 (CHEMBL4294618) Show SMILES CCCCc1nc(C)c(CC(=S)N2CCCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1 Show InChI InChI=1S/C31H35N5O3S/c1-3-4-12-27-32-21(2)26(19-28(40)35-17-8-5-9-18-35)30(37)36(27)20-22-13-15-23(16-14-22)24-10-6-7-11-25(24)29-33-31(38)39-34-29/h6-7,10-11,13-16H,3-5,8-9,12,17-20H2,1-2H3,(H,33,34,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Boryung Pharmaceuticals Co. Ltd. Curated by ChEMBL					Assay Description Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay				Bioorg Med Chem Lett 28: 3155-3160 (2018) Article DOI: 10.1016/j.bmcl.2018.08.036 BindingDB Entry DOI: 10.7270/Q2X63QMZ
					More data for this Ligand-Target Pair