BDBM50467209 CHEMBL4291446

SMILES: COc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1

InChI Key: InChIKey=WWBGDPBRUAWUAY-NRFANRHFSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator/surface receptor (Homo sapiens (Human))	BDBM50467209 (CHEMBL4291446) Show SMILES COc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O5/c1-25(2,3)21(24(30)31)34-23-20(27)12-19(26)22(29-23)33-18-10-16(9-17(11-18)32-4)15-7-5-6-14(8-15)13-28/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human uPA				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50467209 (CHEMBL4291446) Show SMILES COc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O5/c1-25(2,3)21(24(30)31)34-23-20(27)12-19(26)22(29-23)33-18-10-16(9-17(11-18)32-4)15-7-5-6-14(8-15)13-28/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human plasmin				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50467209 (CHEMBL4291446) Show SMILES COc1cc(Oc2nc(O[C@@H](C(O)=O)C(C)(C)C)c(F)cc2F)cc(c1)-c1cccc(CN)c1 |r| Show InChI InChI=1S/C25H26F2N2O5/c1-25(2,3)21(24(30)31)34-23-20(27)12-19(26)22(29-23)33-18-10-16(9-17(11-18)32-4)15-7-5-6-14(8-15)13-28/h5-12,21H,13,28H2,1-4H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abdulaziz University for Health Sciences Curated by ChEMBL					Assay Description Inhibition of human tPA				Bioorg Med Chem Lett 28: 3372-3375 (2018) Article DOI: 10.1016/j.bmcl.2018.09.001 BindingDB Entry DOI: 10.7270/Q24Q7XNF
					More data for this Ligand-Target Pair