null

SMILES: Cl.Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(nc3)C#N)n2)c(C)c1

InChI Key: InChIKey=XSWQUHFEROWPBD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467341 (CHEMBL4294624) Show SMILES Cl.Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(nc3)C#N)n2)c(C)c1 Show InChI InChI=1S/C18H18N8/c1-10-6-11(2)15(12(3)7-10)23-18-25-16(20)24-17(26-18)22-14-5-4-13(8-19)21-9-14/h4-7,9H,1-3H3,(H4,20,22,23,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.784	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of CXCR4 tropic HIV1 UG070 reverse transcriptase infected in human TZM-bl cells				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467341 (CHEMBL4294624) Show SMILES Cl.Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(nc3)C#N)n2)c(C)c1 Show InChI InChI=1S/C18H18N8/c1-10-6-11(2)15(12(3)7-10)23-18-25-16(20)24-17(26-18)22-14-5-4-13(8-19)21-9-14/h4-7,9H,1-3H3,(H4,20,22,23,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.183	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of CCR5 tropic HIV1 ADA5 reverse transcriptase infected in human TZM-bl cells				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467341 (CHEMBL4294624) Show SMILES Cl.Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(nc3)C#N)n2)c(C)c1 Show InChI InChI=1S/C18H18N8/c1-10-6-11(2)15(12(3)7-10)23-18-25-16(20)24-17(26-18)22-14-5-4-13(8-19)21-9-14/h4-7,9H,1-3H3,(H4,20,22,23,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.131	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of CXCR4 tropic HIV1 3B reverse transcriptase infected in human TZM-bl cells				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467341 (CHEMBL4294624) Show SMILES Cl.Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(nc3)C#N)n2)c(C)c1 Show InChI InChI=1S/C18H18N8/c1-10-6-11(2)15(12(3)7-10)23-18-25-16(20)24-17(26-18)22-14-5-4-13(8-19)21-9-14/h4-7,9H,1-3H3,(H4,20,22,23,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.183	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of CCR5 tropic HIV1 VB59 reverse transcriptase infected in human TZM-bl cells				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair