BDBM50467411 CHEMBL4283921

SMILES: Cl.CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)n1

InChI Key: InChIKey=YBFXECOHJCDSDS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50467411 (CHEMBL4283921) Show SMILES Cl.CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)n1 Show InChI InChI=1S/C25H29N5O4/c1-18(31)27-20-9-7-19(8-10-20)23-15-16-26-25(29-23)28-21-11-13-22(14-12-21)34-17-5-3-2-4-6-24(32)30-33/h7-16,33H,2-6,17H2,1H3,(H,27,31)(H,30,32)(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...				Eur J Med Chem 158: 593-619 (2018) Article DOI: 10.1016/j.ejmech.2018.09.024 BindingDB Entry DOI: 10.7270/Q2Z3229Z
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50467411 (CHEMBL4283921) Show SMILES Cl.CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)n1 Show InChI InChI=1S/C25H29N5O4/c1-18(31)27-20-9-7-19(8-10-20)23-15-16-26-25(29-23)28-21-11-13-22(14-12-21)34-17-5-3-2-4-6-24(32)30-33/h7-16,33H,2-6,17H2,1H3,(H,27,31)(H,30,32)(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...				Eur J Med Chem 158: 593-619 (2018) Article DOI: 10.1016/j.ejmech.2018.09.024 BindingDB Entry DOI: 10.7270/Q2Z3229Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50467411 (CHEMBL4283921) Show SMILES Cl.CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)n1 Show InChI InChI=1S/C25H29N5O4/c1-18(31)27-20-9-7-19(8-10-20)23-15-16-26-25(29-23)28-21-11-13-22(14-12-21)34-17-5-3-2-4-6-24(32)30-33/h7-16,33H,2-6,17H2,1H3,(H,27,31)(H,30,32)(H,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...				Eur J Med Chem 158: 593-619 (2018) Article DOI: 10.1016/j.ejmech.2018.09.024 BindingDB Entry DOI: 10.7270/Q2Z3229Z
					More data for this Ligand-Target Pair