null

SMILES: CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCC(=O)Nc1ccc(cc1)C(C)C

InChI Key: InChIKey=UNHDMYZCRLZPEZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50467435 (CHEMBL4291934) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCC(=O)Nc1ccc(cc1)C(C)C Show InChI InChI=1S/C23H31N5O4/c1-6-14-32-22-25-20-19(21(30)27(5)23(31)26(20)4)28(22)13-7-8-18(29)24-17-11-9-16(10-12-17)15(2)3/h9-12,15H,6-8,13-14H2,1-5H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE4B using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase Assay				Eur J Med Chem 158: 517-533 (2018) Article DOI: 10.1016/j.ejmech.2018.09.021 BindingDB Entry DOI: 10.7270/Q2TB19K7
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50467435 (CHEMBL4291934) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCC(=O)Nc1ccc(cc1)C(C)C Show InChI InChI=1S/C23H31N5O4/c1-6-14-32-22-25-20-19(21(30)27(5)23(31)26(20)4)28(22)13-7-8-18(29)24-17-11-9-16(10-12-17)15(2)3/h9-12,15H,6-8,13-14H2,1-5H3,(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE7A using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase Assay				Eur J Med Chem 158: 517-533 (2018) Article DOI: 10.1016/j.ejmech.2018.09.021 BindingDB Entry DOI: 10.7270/Q2TB19K7
					More data for this Ligand-Target Pair